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Medical Microbiology and Parasitology

The Department of Medical Microbiology & Parasitology is at the forefront of pioneering research projects that address critical health challenges. Our research spans a wide array of topics, including the study of infectious diseases, antimicrobial resistance, vaccine development, and parasitic infections. By leveraging advanced technologies and innovative methodologies, our dedicated researchers work tirelessly to unravel the complexities of pathogens and their interactions with hosts. Collaborative efforts with leading institutions and organizations worldwide enhance the impact and scope of our research. Through these projects, we aim to advance scientific knowledge, develop effective treatments, and improve public health outcomes on a global scale.

Research Projects

  • PROF. DR. ZAKUAN ZAINY DERIS

    1. Elucidating the genetic variants of the type V secretion system 5 (T6SS-5) in clinical and environmental strains of Burkholderia pseudomallei and their potential correlation with the clinical course of the human diseases.

    2. In vitro effects of probiotics on the growth of multidrug resistant (MDR) Enterobacteriaceae colonization.

  • PROF. DR. ZEEHAIDA MOHAMED

    1. Development of a multiplex PCR assay for the detection of causative agents for TORCH in neonate.

  • PROF. DR. CHAN YEAN YEAN

    1. Evaluation of in vitro diagnostic assays for the detection of mosquito-borne diseases.

    2. Elucidation of stingless bee honey (Trigona spp.) role as potential immunomodulatory agent in common bcterial community­-acquired pneumonia patient.

    3. Clinical performance evaluation of Real­-Time PCR assay for the detection of Rickettsia, Borrelia, Salmonella typhi and Salmonella paratyphi among patients presented with acute febrile illness.

  • ASSOC. PROF. DR. SITI ASMA’ HASSAN

    1. Catheter related blood stream infections (CRBSI) control through modified CRBSI bundle and patient/ caregiver feeback mechanisms in low resources setting. 

    2. Elucidation of Epstein-Barr virus (EBV) LMPl-30 bp deletion effect on immune checkpoint regulation in EBV-associated cancers (Nasopharyngeal Carcinoma (NPC) and Non-NPC cancers): Implications for immune checkpoints targeted in immunotherapy.

  • ASSOC. PROF. DR. KIRNPAL KAUR BANGA SINGH

    1. Antimicrobial surveillance study (Geran penyelidikan agensi luar).

  • ASSOC. PROF. DR. RAFIDAH HANIM SHOMIAD @ SHUEB

    1. Unravelling the potential inhibitory and immunomodulatory actions of Tualang honey to control chikungunya virus during chronic infection.

    2. Development of quantum dot-based-lateral flow assay for the detection of Hepatitis B.

  • DR. NIK HASZROEL HYSHAM NIK HASHIM

    1. Investigation of the role of mutation in the hepatitis B virus surface antigen and changes to the adaptive immune system as a mechanism for occult hepatitis B virus infection.

  • DR. ZETI NORFIDIYATI SALMUNA @ AYUB

    1. Investigator-driven randomized controlled trial on cefiderocol versus standard therapy for healthcare-associated and hospital-acquired Gram-negative blood stream infection.

  • DR. TUAN NOORKORINA TUAN KUB

    1. The antimicrobial and cytotoxicity activity of Andrographis paniculata intimate wash formulation.

    2. Elucidating the mechanism of Andrographis paniculata targeting TNFR2 expression via activation of p38 pathway in human gastric adenocarcinoma epithelial cells infected by Helicobacter pylori.

  • DR. CHUA WEI CHUAN

    1. Co-infections in hospitalised COVID-19 patients in HUSM: A Study of clinical characteristics, outcomes, laboratory markers, microbiology and metagenomics profile. 

  • DR. MOHD ZULKIFLI SALLEH

    1. Structural determination and characterization of the nonstructural proteins C and V from Nipah virus: towards understanding their roles in the viral pathogenesis and discovery of potential potent drug inhibitors.

    2. Structural analysis of RNA-directed RNA polymerase from Nipah virus via de novo protein modelling: towards understanding its role in the viral replication and discovery of potential potent drug inhibitors.

  • DR. NIK ZURAINA NIK MOHD NOOR

    1. An environmental quality surveillance model for routine risk assessment of melioidosis, leptospirosis and cholera: toward resilient and sustainable ecotourism of Lubuk Yu Waterfall, Pahang.