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DepartmentPathology
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Emailasyilla [AT] usm [DOT] my
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Phone No6453
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Area of Expertise
- Anatomic Pathology with Special Interest in Renal Pathology
- Research Interest : Colorectal Cancer, Female Cancer & Renal Pathology
Personal Information
Academic Qualification
|
Graduated Year |
Academic Qualification |
Place of Training |
| 2007 | MBBS | International Islamaic University Malaysia (IIUM) |
| 2014 | Master of Pathology (Anatomic Pathology) | Universiti Sains Malaysia (USM) |
Working Experience
|
Year |
Working Experience |
Place of Working |
| 2007 | Housemenship & Medical Officer | Universiti Sains Malaysia (USM) |
| 2010 | Trainee Lecturer Anatomic Pathology | Universiti Sains Malaysia (USM) |
| 2014- till present | Pathologist & Mediical Lecturer | Universiti Sains Malaysia (USM) |
| July - September 2022 | Renal Pathology Training | Hospital Kuala Lumpur (HKL) |
Awards
|
Year |
Award |
| 2019 | Second (2nd) Place : Puisi HELWA MERDEKA 2019 |
| 2020 | Excellent Employee Award : Anugerah Perkhidmatan Cemerlang 2019 |
| 2020 | Fundamental Research Grant Scheme (FRGS) Award KPT 2020 |
| 2021 | First Place Best Case Report Award : Diagnostic Conundrum : A case of Thalamic Glioblastoma initially treated as acute infract : National Pathology Conference 2021 |
| 2021 | First Place Best Case Report Award : Sporadic Young onset Colorectal cancer : 2021 International Congress of Pathology and Laboratory Medicine (ICPaLM) 20th Annual General Meeting, College of Pathologists, Academy of Medicine (ICPaLM) 2021 |
| 2021 | SERB-DST sponsored award for workshop on Transmission Electron Microscopy in Life Sciences : Procedure and Applications 2021 |
| 2021 | Excellent Employee Award : Staf Terbaik Jabatan Patologi Pusat Pengajian Sains Perubatan USM Februari 2021 |
| 2022 | Tabung Latihan Akademik : The Columbia Renal Biopsy Course : Columbia University Vagelos |
| 2022 | Career Achievement Award on grade promotion to DU56 |
| 2022 | First Place Oral Research Presentation on FoxP3 Tregulatory cells expression in Colorectal Cancer Patient : 19th Annual Scientific Meeting College of Pathologist |
| 2022 | Thrid Place Research Presentation on Clinicopathological Characteristic of Young Onset Colorectal Cancer in HUSM : 19th Annual Scientific Meeting College of Pathologist |
Research
|
Year Duration |
Research Title |
Grant Resource |
| 2012-2014. | The expression of IGFBP-rP1 in breast and ovarian carcinoma with and without Diabetes Mellitus type 2 | USM (Short Term Grant) |
| 2016-2018 | Expression of DNA Mismatched Repair Protein and BRAF mutation by Immunohistochemistry in Sporadic Young Colorectal Cancer in Kelantan Population | USM (Short Term Grant) |
| 2019-2022 | Understanding the Cellular and Molecular Mechanism of Anti-Cancer Effect of Honey and Curcumin on 1-Methyl-1 Nitrosourea (MNU) Induced Breast Cancer in Rats | Research University Grant |
| 2019-2022 | Putative Crosstalks of GluA1, NK and CB1 Receptors in Targeted Brain Reward Centres of Ketum Alkaloid, Mitragynine in Sensitised Swiss Albino Mice | Research University Grant |
| 2019-2022 | Identification Of Risk Factors Associated With Cancer Prognosis, Disease Survival And Recurrence In Obese Individuals | Long Term Research Grant Scheme (LRGS) |
| 2020-2021 | Assessment of Familial Cancers Samples Collection in Hospital USM towards Molecular Analysis | External Agency (Newcastle University of Medicine Malaysia |
| 2020-2022 | The Facts & Myths of Cervical Cancer | Geran Khas Penerbitan Buku USM |
| 2020-2022 | Glycoproteomic Landscape of Colorectal Cancer Patients for Biomarkers Identification Using Mass Spectrometry Approach | Venn Biosciences Sdn Bhd. External Agencies. |
| 2020-2023 | Elucidating the role of tumour necrosis factor receptor 2 (TNFR2) and FOXP3 regulatory T cells signalling cascades in modulating the progression of sporadic young-onset colorectal cancer. | FRGS Grant. Kementerian Pengajian Tinggi (KPT) |
| 2020-2023 | Exploring novel cancer-associated fibroblast markers of colorectal tumour microenvironment in differentiating the mechanisms of right-sided and left-sided colon cancer. | FRGS Grant. Kementerian Pengajian Tinggi (KPT) |
| 2020-2021 | Expression of FOXP3 and its association with stage and grade of colorectal cancer patients in Hospital Sultanah Bahiyah and Hospital Universiti Sains Malaysia | Grant Penerbitan Siswazah |
| 2021-2024 | Linking Obesity to Cancer: Studying Endometrial Cancer Molecular Heterogeneity of Obese Young Patients Using Targeted NGS | RU TOP-DOWN |
| 2022-2023 | Projek Memperkasa Urutan Traditional Melayu (UTRM_USM) | Community Engagement Project Grant |
Publications:
1. Nur Asyilla Binti Che Jalil, Anani Aila Binti Mat Zin, Nor Hayati Bte Othman, 2015, Prevalence of Cancers of Female Organs among Patients with Diabetes Type 2 in Kelantan, Malaysia: Observations over an 11 Year Period and Strategies to Reduce the Incidence, Asian Pacific Journal of Cancer Prevention, Vol 16, 2015: , 7267-7270 . Main author.
2. Wan Nor Asyikeen Wan Adnan, Nur Asyilla Binti Che Jalil, Anani Aila Binti Mat Zin, Nor Hayati Bte Othman, Siti Azrin Binti Ab Hamid, 2016, Endometrial Cancer in Hospital Universiti Sains Malaysia, Asian Pacific Journal of Cancer Prevention, 17:6. Co-author.
3. Siti Azrin Binti Ab Hamid, Wan Nor Asyikeen Binti Wan Adnan, Nur Asyilla Binti Che Jalil, Anani Aila Binti Mat Zin, Nor Hayati Bte Othman, 2016, Median Survival Time of Endometrial Cancer with Lymphovascular Invasion in Hospital Universiti Sains Malaysia,Malaysian Journal of Medical Sciences, 23:6. Co-author.
4. Anusha Balasubramanian, Irfan Bin Mohamad, Nur Asyilla Binti Che Jalil, Anani Aila Binti Mat Zin, Wan Faiziah Binti Wan Abdul Rahman, 2013, Mucoepidermoid carcinoma of the thyroid gland, Brunei International Medical Journal, 9:3. Co-author.
5. W.Faiziah, N.Asyilla, Hadif Samsudin, Siti Rahmah, 2016, Duodenal Mass from Heterotopic Pancreas: A Unique Cause of Septic Shock., Annals Academy of Medicine Singapore, 45: , (Impact Factor : 1.041). Co-author..
6. Alfred K-y Lam, Rahman WFWA, Nur Asyilla CJ, Hadif Shamsudin, Siti Rahmah H.I.M ,2016, Heterotopic pancreatitis complicated with septic shock: An unusual presentation,PATHOLOGY - The Journal of Royal Colege of Pathologists of Australasia, 48:S1, S1 (Impact Factor : 2.968) . Co-author.
7. Chew Shiun Chuen, Mohd Khairi Bin Md Daud, Nur Asyilla Binti Che Jalil, Hilma Hazmi, 2017, Relapse of B-cell acute lymphoblastic leukaemia presenting as right aural polyp with facial and mandibular nerve palsy, Medical Journal of Malaysia, 72: Coauthor.
8. Wan Faiiziah Wan Abdul Rahman, Nur Asyilla Binti Che Jalil, Irfan Bin Mohamad, Mohd Khairi Bin Md Daud, 2014, Hamartomatous polyp of the tonsil: a case report, Archives of Orofacial Sciences, 9:2, Co-author.
9. Ahmad Razif Omar, Khairy Shamel Teo, Ariffin Nasir, Nur Asyilla Che Jalil, Chandran Ndarajan and Mokhtar Ibrahim, 2018, Bilateral Orbital Peripheral Primitive Neuroectodermal Tumor: A Case Report, JOJ Ophthalmology Journal, Research Article Volume 6 Issue 5 - August 2018. Co-author.
10. Siti Norasikin Mohd Nafi, Ab Hamid SITI AZRIN, Anani Aila MAT ZIN, Nor Hayati OTHMAN Nur Asyilla Binti Che Jalil, .Expression of IGFBP-rP1 in ovarian and breast cancers in association with diabetes mellitus status Malaysian J Pathol 2019; 41(1) : 33 –39 . Corresponding author.
11. Azihan Z, Wong MPK, Zubaidah S, Asyilla CJ, Sharifah ETS, 2019, Peritoneal Tuberculosis - a Diagnostic Challenge in Acute Abdomen, Surgical Chronicles. 24/2: 88-90. Co-author.
12. Banik U, Ahamed S, Latt SS, Che Jalil NA, Wan Abdul Rahman WF, Othman NH. Pattern of Histopathological Alterations in N-methyl-NNitrosourea (MNU) Induced Breast Cancer in Female Sprague Dawley (SD) Rats Treated with Crude Honey. Pertanika Journal of Science & Technology. 2020 Oct 1;28(4). Co-author.
13. Nur Asyilla Che Jalil , Wan Faiziah Wan Abdul Rahman, Ahmad Hadif Zaidin Samsudin, Maya Mazuwin Yahya. Metastatic leiomyosarcoma of the thyroid. Malaysian Journal of Pathology. First Author. Accepted 16.9.2020. Main author.
14. Zubaidah Saizul, Siti Azrin Ab Hamid, Andee Dzulkarnaen Zakaria, Wan Faiziah Wan Abdul Rahman, Aniza Hassan, Nur Asyilla Che Jalil . BRAF and Mismatch Repair (MMR) Proteins Expression in Sporadic Early Onset Colorectal Cancer in Kelantan. Oman Medical Journal. Corresponding Author. Accepted 17.10. 2020
15. Farahlina Baba , Ahmad Hadif Zaidin Samsudin , Wan Azman Wan Sulaiman , Wan Faiziah Wan Abdul Rahman, Nur Asyilla Che Jalil. Extensive Basal Cell Adenocarcinoma Involving Minor Salivary Gland of the Hard Palate: A Rare Entity. Archives Of Orofacial Sciences Accepted 6.10.2020. Corresponding Author
Copyright / Intellectual Properties
1. ABC of Immunohistochemistry (Pressure Cooker Method) , MyIPO : LY2018002612. 02.07.2018. Co-author.
2. Teaching & Learning For M.Path (Anatomik Pathology). MyIPO : LY2019000424. 14.02.2019. Main-author.
3. Perkhidmatan Aspirasi Jarum Halus Sitologi (Fine Needle Aspiration Cytology). MyIPO : LY2018004459. 24.09.2018. Co-author.
4. Perkhidmatan Ujian Sitopatologi. MyIPO : LY2018004460. 24.09.2018. Co-author.
5. Survey on Master of Pathology Curriculum Univeristi Sains Malaysia for Supervisor. MyIPO : LY2019000427. 14.02.2019. Main-author.
6. Survey on Master of Pathology Curriculum Univeristi Sains Malaysia for Pathologist and Mpath Student. MyIPO : LY2019000426.14.02.2019. Main-author.
7. Survey Aanalysis on Master of Pathology Curriculum Univeristi Sains Malaysia for Supervisor.2019. MyIPO : LY2019006124. Main-author.
8. Survey Analysis on Master of Pathology Curriculum Universiti Sains Malaysia for Pathologist and Mpath Student.2019. MyIPO : LY2019006123. Main-author.
9. Sajak : Dia Professor Hati Kami. Literary. 31.01.2020. MyIPO : LY2020000341. Mainauthor.
10. Puisi (1) Susuk Tersembunyi & (2) Wanita itu Dia. Literary. 31.01.2020. MyIPO : LY2020000340. Main-author.
11. Video Pendek SajaK Perpisahan Prof Hasnan Jaafar. Literary. 07.02.2020. MyIPO : FM2020000451. Main-author.
12. Renal Biopsy Histopathology Report Version 2, July 2020. Literary. 01.09.2020. MyIPO : LY2020003463. Main-author.
13. Prosedur Terkini Pewarnaan H&E, Pewarnaan Khas dan Imunofluresen Biopsi Renal.23.11.2020. Literary . MyIPO : LY2020005892. Main-author.
Conference Presentation
1. Monophasic Synovial Sarcoma with Extensive Psammomotous Calcification: A case Report. International, 17th International Conference on Medical and Health Sciences, Health Campus Unversiti Sains Malaysia Kelantan. 27.05.2012 – 28.05.2012. Main-author.
2. Expression Of IGFBP-rP1 In Ovarian And Breast Carcinoma In Patient With And Without Diabetes Mellitus Type 2, National, 19 th National Conference on Medical and Health Sciences, School of Dental Sciences Health Campus Unversiti Sains Malaysia. 07.09.2014 - 08.09.2014. Main-author.
3. The Prevalence Diabetes Type 2 Among Patients Having Female Cancers in Kelantan, International. 18th International Conference On Medical Science & Health Sciences(Icmhs),Renaisance Hotel Kota Bharu Kelantan Malaysia. 22.05.2013 – 24.05.2013. Main-author.
4. Heterotopic Pancreatitis Complicated with Septic Shock : An usunal presentation. International Working Paper Presentation, APIAP 2015 Brisbane Australia, 04.06.2015 – 07.06.2015. Co-author.
5. Proportion of Male Genital Tract Pathology : Observation over a 5 years Period in Hospital Universiti Sains Malaysia. International Working Paper Presentation. The International Academy of Pathology Malaysian Division (IAPMD) Annual Scientific Meeting Kota Kinabalu 2018, Shangri-La Tanjung Aru Spa & Resort Kota Kinabalu Sabah, 27.10.2018 – 28.10.2018. Co-author.
6. Warthin Tumour Subtype Poor Stroma: A diagnostic challenge in frozen section, International Working Paper Presentation, International Academy of Pathology Malaysian Division (IAPMD) 4th Annual Meeting. Grand River View Hotel. 9.09.2017-11.09.2017. Corresponding author.
7. BRAF and Mismatch Repair Proteins Expression by Immunohistochemistry in Sporadic Young Colorectal Carcinoma in Kelantan Population, International Working Paper Presentation. International Conference Medical & Health Sciences 2019, Grand Renai, 25.08.2019 26.08.2019. Corresponding author.
8. Clinicopathological Analysis And Mismatch Repair Proteins Pattern In Hereditary Nonpolyposis Colorectal Cancer (HNPCC) Of Malay Patients, International Working Paper Presentation. International Conference Medical & Health Sciences 2019. Grand Renai. 25.08.09 - 26.08.2019. Co-author.
2. Involvement of CB1 receptor in Motor Coordination Alteration by Using Rotarod of flow doses Mitragynine-sensitised Albino Swiss Mice. Malaysian Society Neuroscience. 8.12.2019. Co-author.
3. Endocan-microvascular density as a biomarker of neoangiogenesis in primary ovarian carcinoma,03/03/2021 -05/03/2021,2021 International Congress of Pathology & Laboratory Medicine (ICPaLM) and 20th Annual General Meeting of College of Pathologists, Academy of Medicine of Malaysia, Virtual Conference(International)
4. The Anti-cancer Effects of Curcumin on Breast Carcinogenesis in Rats: A Preliminary Study,03/03/2021 – 05/03/2021, 2021 International Congress of Pathology & Laboratory Medicine (ICPaLM) and 20th Annual General Meeting of College of Pathologists, Academy of Medicine of Malaysia, Virtual Conference(International)
5. Association of Body Mass Index with Clinicopathological Features of Colorectal Cancer cases in HUSM,06/04/2021 -08/04/2021,AOCO-MASO 2021 – Asia Oceania Congress on Obesity and MASO Scientific Conference 2021,Virtual Conference(National)
6. Sporadic young-onset colorectal cancer : Two cases from Hospital Universiti Sains Malaysia Experience,03/03/2021 -05/03/2021,2021 International Congress of Pathology & Laboratory Medicine (ICPaLM) and 20th Annual General Meeting of College of Pathologists, Academy of Medicine of Malaysia, Virtual Conference(International)
Other Publication
1. Patogenesis of Covid-19: Suatu Kembara Sains Yang Menuntut Dsiplin Diri.http://covid19.kk.usm.my/index.php/artikel/bacaan-umum/24-jangkitan-covid-19-sebuahkembara-sains-menuntut-disiplin-diri. 27.04.2020. Co-Author.
2. Kenali Coronavirus (COVID-19): Bicara Tentang Dia. http://covid19.kk.usm.my/index.php/artikel/bacaan-umum/29-novel-coronavirus-covid-19-bicara-asa-tentang-dia. 27.04.2020. Corresponding Author
3. Clinicopathological Analysis and Mismatch Repair Protiens Pattern in Hereditary Nonpolyposis Colorectal cancer of Malay Patient in Kelantan Population Conference Proceeding. Malaysian Journal of Medical Sciences. 01.04.2020. Co-Author.
4. BRAF and Mismatch Repair (MMR) Proteins Expression in Sporadic Early Onset Colorectal Cancer in Kelantan. Oman Medical Journal. Conference Proceeding. Malaysian Journal of Medical Sciences. 01.04.2020. Corresponding Author
Collaboration / Networking
1. UMK. Deep Burial Effect of Formalin Fixed Pathological Waste Disposal on the groundwater & soil collaboration with researchers from University Malaysia Kelantan
2. IAPMD (International Academy of Pathology, Malaysian Division). Life member.
3. FAMA (Lembaga Pemasaran Persekutuan [FAMA] Kelantan). Kajian Kesan MaduTualang Terhadap Barah Payudara Menggunakan Model Tikus.
Publication
Supervision
RESEARCH SUPERVISION
|
Topic (Dissertation / Thesis topic) |
Level (PhD / MSc / Mixed Mode / Course work / Pro Course) |
Status (On-going / graduated status) |
Year (By year) |
| NURUL HAKIMAH BINTI MOHD SALIM : Elucidating the Role of Tumour Necrosis Factor Receptor 2 (TNFR2) and Regulatory T Cells Signalling Cascades in Modulating the Progression of sporadic young-onset colorectal cancer : MAIN SUPERVISOR | PhD | On-going | 2022 |
| Martina binti Mohd Irwan Khoo : Understanding the Cellular and Molecular Mechanism and Anticancer Effect of Honey and Curcumin on 1-Methyl-1 Nitrosourea (MNU) Induce Breast Cancer in Rats : Co-supervisor |
PhD |
On-going
|
2020 |
| Urmila Banik : Understanding the Cellular and Molecular Mechanism and Anticancer Effect of Honey on breast Cancer Cell Line. Co-supervisor. |
PhD |
On-going |
2019 |
| Zaida Zakaria : Understanding The Mechanism of Malaysian Bee Bread on Oxidative Stress-Induced Fatty Liver Disease In High-Fat Diet- Induced Obese Male Rats. Co-Supervisor. | PhD | On-going | 2020 |
| Zaidatul Akmal binti Othman : Understanding the Effects of Bee Bread on Cardiovascular Changes in Obese Rats. Co-Supervisor. | PhD | Graduated | 2022 |
| ISAH RILWANU TSAMIYA : Foxp3 in young Colorectcal Cancer. Co-supervisor. | PhD | On-going | 2021 |
| NG PHEI YING : The Role of ApoB100 and KRAS Mutation in Obesity-Related Colorectal Carcinoma. Co-Supervisor | Master | On-going | 2021 |
| Tan Shong Sheng : CEA Density is a new tool for predictive factor for Colorectal Carcinoma | MMed | On-going | 2020 |
| Hidayati Husainy Binti Hasbullah : KRAS Gene Mutational Profiles among Colorectal Cancer(CRC) Patients in Hospital Universiti Sains Malaysia (HUSM). Co-supervisor. | MPath 2 (Genetic) | On-going | 2021 |
| Sobry Bin Hashim : Expression of FOXP3 tumour infiltrating lymphocytes in HER2 positive breast cancer and their association with clinicopathological features. Co-supervisor. | MPath 2 (Anatomic Pathology) | On-going | 2021 |
| Dahziela Binti Hj Yunus : PERITUMOURAL BUDDING IN COLORECTAL CARCINOMA,IT’S ASSOCIATED FACTORS AND THE POTENTIAL AS AN INDEPENDENT HISTOPATHOLOGICAL PARAMETER PREDICTOR. Co-supervisor. | MPath 2 (Anatomic Pathology) | On-going | 2021 |
| Md Najmi Md Nasir : Expression of FOXP3 and its Association with Stage and Grade of Colorectal cancer patients. Main-supervisor. | MPath 2 (Anatomic Pathology) | Graduated | 2022 |
| Farahlina Baba : Evaluation of Endocan MVD in Primary Epithelial Ovarian Cancer and Its Association with the clinicopathological Features. Main-supervisor. | MPath 2 (Anatomic Pathology) | Graduated | 2021 |
| Azam Hilmi Mohd Zain : Development of a new Scoring System of Nuclear Pleomorphism based on Bloom Richardson Grading System in Invasive Breast Cancer. Co-supervisor. | MPath 2 (Anatomic Pathology) | Graduated | 2021 |
| Farhana binti Mhammad Mohaidin : The Evaluation Of Program Death 1 (PD-1) and PD-1 Ligand (PD-L1) Expressions in Histological Subtypes of Primary Extranodal Non Hodgkin Lymphoma. Co-supervisor. | MPath 2 (Anatomic Pathology) | Graduated | 2020 |
| Norhafizah binti Abdul Rahim : Clinicopathologival Analysis of Malay Hereditary non Polyposis Colorectal Carcinoma in HNPCC and its association with MMR protein Expression. Co-supervisor. | MPath 2 (Anatomic Pathology) | Graduated | 2019 |
| Raja Zubaidah Binti Raja Mohd Rasi : Accuracy of the Thyroid Fine Needle Aspiration Cytology by Using Bethesda System : A hospital Based Study. Main-supervisor. | MPath 2 (Anatomic Pathology) | Graduated | 2018 |
| Zubaidah binti Saizul. MPath : Expression of DNA Mismatched Repair Protiens and BRAF mutation by Immunohistochemistry in Young-Onset Colorectal Cancer in Kelantan Population. Main-supervisor. | MPath 2 (Anatomic Pathology) | Graduated | 2019 |
| WAN HANIS BINTI WAN ZAKKHRY : A study to validate the effect of enzymatic treatment using Proteinase K in FFPE renal biopsy tissue on IF staining detection and investigation on the potential of DNA-Aptamer as alternative synthetic bioreceptor in renal pathology diagnostic | MPath 2 (Anatomic Pathology) | On-going | 2022 |
CLINICAL / ACADEMIC / LAB SUPERVISION
|
Topic (Speciality / Field) |
Level (Pro Course / MMed / Fellowship) |
Status (Completed - Number of students supervised) |
Year (By year) |
|
Industrial Students : Laboratory Supervision |
Undergraduate | Completed - 2 | 2014 |
|
Industrial Students : Laboratory Supervision |
Undergraduate | Completed - 2 | 2015 |
| Industrial Students : Laboratory Supervision | Undergraduate | Completed - 1 | 2016 |
| Master of Pathology Phase 1 : Academic Supervision | MPath 1 | Completed - 1 | 2016 |
| Clinical Attachment Student | Post-graduate | Competed - 1 | 2020 |
| Industrial Students : Laboratory Supervision | Undegraduate | Completed - 4 | 2017 |
| Master of Pathology Phase 1 : Academic Supervision | MPath 1 | Completed - 1 | 2017 |
| Master of Pathology Phase 1 : Academic Supervision | MPath 1 | Completed - 2 | 2019 |
| Industrial Students : Laboratory Supervision | Undegraduate | Completed - 4 | 2020 |
| Master of Pathology Phase 1 : Academic Supervision | MPath 1 | Completed - 1 | 2020 |
| Industrial Students : Laboratory Supervision | Undergraduate | Completed -4 | 2021 |
| Master of Pathology Phase 1 : Academic Supervision | MPath 1 | Completed - 1 | 2021 |
| Industrial Students : Laboratory Supervision | Undegraduate | Completed - 2 | 2022 |
| Master of Pathology Phase 1 : Academic Supervision | MPath 1 | Completed - 2 | 2022 |
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